Plastic mulches are widely used in U.S. vegetable production to cut costs and improve efficiency. However, polyethylene, the principal ingredient of plastic mulches, is a poorly degradable material causing significant pollution. Biodegradable mulches, especially those made from local waste materials such as low-grade cotton, offer a sustainable alternative by reducing pollution, enhancing soil health, and supporting circular economy principles. This study aims to evaluate two different types of low-grade cotton mulches in comparison to commercially available plastic and biodegradable plastic mulches in Jalapeño pepper production. Five mulch treatments, including a no-mulch control, were arranged in a randomized complete block design with four replications. The assessment focuses on mulch decomposition, plant biomass, crop yield, and weed suppression.