Snap bean (Phaseolus vulgaris L.) is a vital crop in Florida, but it is highly vulnerable to low-oxygen (O₂) stress in soil and phosphorus (P) deficiency, particularly in regions utilizing deep well irrigation. The objective of this study was to evaluate the effects of liquid O₂ and P fertigation on plant growth, pod yield, and nutrient uptake under field conditions. A Randomized Complete Block Design (RCBD) with four replications was employed, testing two rates of liquid O₂ (0 and 45 kg ha⁻¹ as hydrogen peroxide, H₂O₂) and five levels (0, 90, 135, 180, and 225 kg ha⁻¹) of liquid P as 0-54-0 phosphoric acid (H₃PO₄). Key variables assessed included plant growth, P uptake, pod yield, and soil properties to evaluate the effectiveness of fertigation in promoting plant performance and nutrient uptake. The results indicated that both liquid O₂ and P applications enhanced plant growth and pod yield, with the highest pod yield achieved from the combination of 45 kg ha⁻¹ of liquid O₂ and 225 kg ha⁻¹ of liquid P. Pearson correlation analysis revealed strong associations between plant growth, pod yield, and nutrient uptake. Principal component analysis (PCA) confirmed the significant effects of liquid O₂ and P fertigation on growth parameters and pod yield. This study concludes that liquid O₂ fertigation alleviates soil hypoxia, improves P use efficiency, and boosts crop productivity, offering a promising and cost-effective solution for optimizing snap bean cultivation.